For tubal patency test using ultrasound.
Hysterosalpingo-Foam Sonography (HyFoSy), using ExEm-gel for creating stable foam, was developed as an office procedure for tubal patency testing. The technique was tested in a prospective laparoscopy-controlled study. Hysterosalpingo Contrast Sonography (HyCoSy) is, compared to the Hysterosalpingography (HSG), a first-line investigation to diagnose female tubal subfertility. For tubal patency testing, HyFoSy with ExEm-gelfoam is performing better then HyCoSy with saline, in terms of accuracy.
ExEm-gel is considered to be safe, as the components have been used intravenously and in the abdominal cavity for other medical purposes. There are no known serious side effects and have been found to be less painful than HSG. HyFoSy may improve women’s chances of pregnancy, although this has to be investigated further.